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af2126  (R&D Systems)


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    Structured Review

    R&D Systems af2126
    Af2126, supplied by R&D Systems, used in various techniques. Bioz Stars score: 92/100, based on 8 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/af2126/product/R&D Systems
    Average 92 stars, based on 8 article reviews
    af2126 - by Bioz Stars, 2026-03
    92/100 stars

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    Image Search Results


    ( A ) Relative mRNA expression levels of pan CHL1, and isoforms 1 and 2 in primary GIST, ( B ) Western blot analyses of CHL1 protein expression in primary tumors and metastases.

    Journal: Oncotarget

    Article Title: Expression and serum levels of the neural cell adhesion molecule L1-like protein (CHL1) in gastrointestinal stroma tumors (GIST) and its prognostic power

    doi: 10.18632/oncotarget.27525

    Figure Lengend Snippet: ( A ) Relative mRNA expression levels of pan CHL1, and isoforms 1 and 2 in primary GIST, ( B ) Western blot analyses of CHL1 protein expression in primary tumors and metastases.

    Article Snippet: A polyclonal antibody raised against the extracellular domain of human CHL1 (CHL1/L1CAM-2 (AF2126; R&D Systems, USA) was used.

    Techniques: Expressing, Western Blot

    ( A ) Recurrence free survival for local CHL1 expression, ( B ) Overall survival for local CHL1 expression, ( C ) Recurrence free survival for serum CHL1 levels with cut-off values at 11.0 ng/ml, ( D ) Overall survival for serum CHL1 levels with cut-off values at 11.0 ng/ml, ( E ) Recurrence free survival for serum CHL1 levels with cut-off values at 14.5 ng/ml, ( F ) Overall survival for serum CHL1 levels with cut-off values at 14.5 ng/ml.

    Journal: Oncotarget

    Article Title: Expression and serum levels of the neural cell adhesion molecule L1-like protein (CHL1) in gastrointestinal stroma tumors (GIST) and its prognostic power

    doi: 10.18632/oncotarget.27525

    Figure Lengend Snippet: ( A ) Recurrence free survival for local CHL1 expression, ( B ) Overall survival for local CHL1 expression, ( C ) Recurrence free survival for serum CHL1 levels with cut-off values at 11.0 ng/ml, ( D ) Overall survival for serum CHL1 levels with cut-off values at 11.0 ng/ml, ( E ) Recurrence free survival for serum CHL1 levels with cut-off values at 14.5 ng/ml, ( F ) Overall survival for serum CHL1 levels with cut-off values at 14.5 ng/ml.

    Article Snippet: A polyclonal antibody raised against the extracellular domain of human CHL1 (CHL1/L1CAM-2 (AF2126; R&D Systems, USA) was used.

    Techniques: Expressing

    Association of clinicopathological characteristics of GIST patients with local CHL1 expression and serum CHL1 levels (cut-off 11.0 ng/ml)

    Journal: Oncotarget

    Article Title: Expression and serum levels of the neural cell adhesion molecule L1-like protein (CHL1) in gastrointestinal stroma tumors (GIST) and its prognostic power

    doi: 10.18632/oncotarget.27525

    Figure Lengend Snippet: Association of clinicopathological characteristics of GIST patients with local CHL1 expression and serum CHL1 levels (cut-off 11.0 ng/ml)

    Article Snippet: A polyclonal antibody raised against the extracellular domain of human CHL1 (CHL1/L1CAM-2 (AF2126; R&D Systems, USA) was used.

    Techniques: Expressing

    Serum CHL1 levels in GIST ( A ) Serum CHL1 levels of patients with GIST and healthy controls. ( B ) Receiver operating characteristic (ROC) curves of serum CHL1 levels for detecting GIST.

    Journal: Oncotarget

    Article Title: Expression and serum levels of the neural cell adhesion molecule L1-like protein (CHL1) in gastrointestinal stroma tumors (GIST) and its prognostic power

    doi: 10.18632/oncotarget.27525

    Figure Lengend Snippet: Serum CHL1 levels in GIST ( A ) Serum CHL1 levels of patients with GIST and healthy controls. ( B ) Receiver operating characteristic (ROC) curves of serum CHL1 levels for detecting GIST.

    Article Snippet: A polyclonal antibody raised against the extracellular domain of human CHL1 (CHL1/L1CAM-2 (AF2126; R&D Systems, USA) was used.

    Techniques:

    Prognostic value of serum CHL1 levels for recurrence free survival

    Journal: Oncotarget

    Article Title: Expression and serum levels of the neural cell adhesion molecule L1-like protein (CHL1) in gastrointestinal stroma tumors (GIST) and its prognostic power

    doi: 10.18632/oncotarget.27525

    Figure Lengend Snippet: Prognostic value of serum CHL1 levels for recurrence free survival

    Article Snippet: A polyclonal antibody raised against the extracellular domain of human CHL1 (CHL1/L1CAM-2 (AF2126; R&D Systems, USA) was used.

    Techniques:

    Expression of CHL1 and NrCAM in pediatric neuroblastoma. Representative examples of CHL1 positive (A) and CHL-1 negative (B) (magnification x100) as well as NrCAM positive (C) and NrCAM negative (D) immunostaining (magnification x200).

    Journal: Open Medicine

    Article Title: CHL1 and NrCAM are Primarily Expressed in Low Grade Pediatric Neuroblastoma

    doi: 10.1515/med-2019-0109

    Figure Lengend Snippet: Expression of CHL1 and NrCAM in pediatric neuroblastoma. Representative examples of CHL1 positive (A) and CHL-1 negative (B) (magnification x100) as well as NrCAM positive (C) and NrCAM negative (D) immunostaining (magnification x200).

    Article Snippet: Afterwards, the primary antibody either specific for CHL1 (goat, polyclonal antibody: AF2126, R&D Systems, MN, USA) or NrCAM (goat anti-human NrCAM antibody: AF2034, R&D Systems, MN, USA,) was applied at 37°C and pH 9.1 for 60 minutes.

    Techniques: Expressing, Immunostaining

    Kaplan-Meier survival curves for overall and event-free survival. No association was found for CHL1-expression (A/B). Survival rates were better by trend in children with NrCAM positive tumors (C/D) but without statistical significance (p=0.07 and p=0.06).

    Journal: Open Medicine

    Article Title: CHL1 and NrCAM are Primarily Expressed in Low Grade Pediatric Neuroblastoma

    doi: 10.1515/med-2019-0109

    Figure Lengend Snippet: Kaplan-Meier survival curves for overall and event-free survival. No association was found for CHL1-expression (A/B). Survival rates were better by trend in children with NrCAM positive tumors (C/D) but without statistical significance (p=0.07 and p=0.06).

    Article Snippet: Afterwards, the primary antibody either specific for CHL1 (goat, polyclonal antibody: AF2126, R&D Systems, MN, USA) or NrCAM (goat anti-human NrCAM antibody: AF2034, R&D Systems, MN, USA,) was applied at 37°C and pH 9.1 for 60 minutes.

    Techniques: Expressing

    CHL1 expression as well as clinical, pathologic and molecular characteristics of the analysed neuroblastoma tissue samples. Statistical analyses by using cross-tables, two-sided Fisher´s and Chi-squared test.

    Journal: Open Medicine

    Article Title: CHL1 and NrCAM are Primarily Expressed in Low Grade Pediatric Neuroblastoma

    doi: 10.1515/med-2019-0109

    Figure Lengend Snippet: CHL1 expression as well as clinical, pathologic and molecular characteristics of the analysed neuroblastoma tissue samples. Statistical analyses by using cross-tables, two-sided Fisher´s and Chi-squared test.

    Article Snippet: Afterwards, the primary antibody either specific for CHL1 (goat, polyclonal antibody: AF2126, R&D Systems, MN, USA) or NrCAM (goat anti-human NrCAM antibody: AF2034, R&D Systems, MN, USA,) was applied at 37°C and pH 9.1 for 60 minutes.

    Techniques: Expressing, Amplification